Treats high blood pressure, fluid retention (edema) and other conditions such as hypokalemia (low potassium levels). Helps the body hold on to potassium, an important mineral in the body. Removes a small amount of extra fluid from the body. Essential hypertension; edematous conditions, including congestive heart failure, cirrhosis of the liver (with or without ascites) and the nephrotic syndrome; idiopathic edema; diagnosis and treatment of primary aldosteronism; as adjunctive therapy in malignant hypertension; in hypokalemia when other measures are considered inappropriate or inadequate; prophylaxis of hypokalemia in patients taking digitalis when other measures are considered inadequate or inappropriate.

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ALDACTONE may cause dizziness or blurred vision. Watch for signs of dehydration such as dry mouth or thirst. You may experience nausea, vomiting, loss of appetite, fatigue, sleeplessness or nasal congestion the first few days as your body adjusts to the medication. If any of these effects persist or worsen, inform your doctor promptly. Unlikely, but report promptly if you develop: yellowing of the skin, deepening of the voice, sore throat, weakness, irregular pulse, persistent cough, decreased sexual ability, change in the amount of urine, increased breast size, breast soreness. In the unlikely event you have an allergic reaction to this drug, seek immediate medical attention. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, breathing trouble. If you notice other effects not listed above, contact your doctor or pharmacist.

Take this exactly as prescribed. Do not skip doses or increase the dose without your doctor's approval. Take with food or milk to minimize stomach upset. Because ALDACTONE may increase urination, avoid taking a dose right before bedtime.

ALDACTONE can raise your body's potassium levels. This is more likely to occur in people with kidney problems, diabetes, in elderly patients, or if the patient is severely ill. Potassium levels must be closely monitored in people with any of these problems or illnesses. If not treated, high potassium levels can be fatal. If you develop any of the following symptoms, notify your doctor immediately: muscle weakness, irregular heartbeat.

Tell your doctor your medical history especially of: kidney or liver disease, urinary problems, diabetes, sodium or potassium imbalances, any allergies. Because ALDACTONE changes your fluid balance, you may feel dizzy if you change from a lying to a standing position too rapidly. Avoid this by rising slowly. If ALDACTONE makes you dizzy, use caution while engaging in activities that require alertness such as driving or using machinery. Before having surgery, including dental surgery, tell the doctor you take spironolactone. ALDACTONE should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. ALDACTONE is excreted into breast milk and the manufacturer of ALDACTONE recommends that breast-feeding not be undertaken while using it. Consult your doctor before breast-feeding.

Tell your doctor of all medications you may use (both prescription and nonprescription) especially of: other diuretics ("water pills" such as amiloride or triamterene); lithium; digoxin; potassium supplements; cyclosporine; mitotane; ACE inhibitors (e.g., lisinopril, captopril, enalapril); NSAIDs (e.g., ibuprofen, naproxen). Aspirin may decrease the effects of spironolactone. Many nonprescription products contain aspirin. Consult your pharmacist if you are uncertain your nonprescription medicines contain aspirin. ALDACTONE may increase your potassium levels. Consult your doctor or pharmacist before using potassium-containing products (salt substitutes or potassium supplements) or large amounts of potassium-containing foods (e.g., bananas, potatoes). Do not start or stop any medicine without doctor or pharmacist approval.

If overdose is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, weakness, and lightheadedness.

If you miss a dose, take as soon as remembered; do not take if it is almost time for the next dose, instead, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.