Prilosec is prescribed for the short-term treatment (4 to 8 weeks) of stomach ulcer, duodenal ulcer (near the exit from the stomach), and erosive esophagitis (inflammation of the esophagus), and for the treatment of heartburn and other symptoms of gastroesophageal reflux disease (backflow of acid stomach contents into the canal leading to the stomach). It is also used to maintain healing of erosive esophagitis and for the long-term treatment of conditions in which too much stomach acid is secreted, including Zollinger-Ellison syndrome, multiple endocrine adenomas (benign tumors), and systemic mastocytosis (cancerous cells). Combined with the antibiotic clarithromycin (Biaxin) (and sometimes with the antibiotic amoxicillin as well), Prilosec is also used to cure patients whose ulcers are caused by infection with the germ H. pylori.

Reflux Oesophagitis
Losec is used to treat oesophagitis or reflux disease. This can be caused by "washing back" (reflux) of food and acid from the stomach into the gullet (oesophagus).
Reflux can cause a burning sensation in the chest rising up to the throat, also known as heartburn.
Losec is also used to help stop reflux oesophagitis coming back or relapsing.

Zollinger-Ellison Syndrome
Losec is also used to treat a rare condition called Zollinger-Ellison syndrome, where the stomach produces large amounts of acid, much more than in ulcers or reflux disease.

How Losec works

Losec is a type of medicine called a proton-pump inhibitor.
Losec works by decreasing the amount of acid made by the stomach, to give relief of symptoms and allow healing to take place. This does not stop food being digested in the normal way.
Your doctor will have explained why you are being treated with Losec and told you what dose to take.
Follow all directions given to you by your doctor carefully. They may differ from the information contained in this leaflet.
Your doctor may prescribe this medicine for another use. Ask your doctor if you want more information.
There is no evidence that Losec is addictive.

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Tell your doctor or pharmacist as soon as possible if you do not feel well while you are taking Losec.
Losec helps most people with stomach or duodenal ulcers or reflux disease, but it may have unwanted side effects in a few people.
All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor or pharmacist to answer any questions you may have. Tell your doctor if you notice any of the following and they worry you:

- constipation
- nausea
- diarrhoea
- headache
- skin rash

These are all mild side effects of Losec.

Some people may notice:
- muscle pain or weakness
- dizziness
- "pins and needles"
- changes in sleep patterns
- mood changes
- increase in breast size (males)
- fever
- increased bruising
Tell your doctor if you think you have any of these effects or notice anything else that is making you feel unwell.
Losec does not contain gluten.

You must tell your doctor if:

1. you have any allergies to

- any medicine containing a proton-pump inhibitor
- ingredients listed at the end of this leaflet
- any other medicines, foods, dyes or preservatives.

If you have an allergic reaction, you may get a skin rash, difficulty in breathing, hayfever, or feel faint.

2. you have any other medical conditions

Taking other medicines
- Tell your doctor if you are taking any other medicines, including:

- phenytoin
- warfarin
- diazepam
- ketoconazole, itraconazole

- other medicines that you buy at the chemist, supermarket or health food shop

These medicines may be affected by Losec or may affect how well it works.
Your doctor or pharmacist can tell you what to do if you are taking any other medicines.

- If you have not told your doctor about any of these things, tell them before you take any Losec.

- Take one Losec capsule each day, unless your doctor has told you otherwise.
The dose of Losec is usually 20 mg a day, but may vary from 10 mg to 40 mg a day depending on what condition you are being treated for and how severe it is.
Swallow Losec capsules whole with a glass of water.
If the granules in the capsules are chewed or crushed they won't work properly.

- Take Losec at about the same time each day.
Keeping a regular time for taking Losec will help to remind you to take it. In most patients, Losec relieves symptoms rapidly and healing is usually complete within 4 weeks. Although Losec heals ulcers very successfully, it may not prevent them recurring at a later date. Losec can be taken to prevent these relapses.

- Tell your doctor if your symptoms return. It is possible that taking Losec and antibiotics may not kill Helicobacter pylori. You may need treatment with Losec and different antibiotics.

- It does not matter whether you take Losec with food or on an empty stomach. If you forget to take it If you forget to take a dose, take it as soon as you remember, and then go back to taking it as you would normally.
If it is almost time for your next dose, skip the dose you missed and take your next dose when you are meant to. Do not take a double dose to make up for the dose that you missed. If you have trouble remembering when to take your medicine, ask your pharmacist for some hints.

When you must not use it
- Do not use Losec if you are pregnant or breastfeeding unless your doctor says so. Ask your doctor about the risks and benefits involved.

We do not know if it is safe for you to take it while you are pregnant. It may affect your baby.
It is not known if your baby can take in Losec from breast milk if you are breastfeeding.

- Do not give Losec to children.
There is no specific information about use in children, so Losec is not recommended in children.

- Do not use Losec after the use by (expiry) date printed on the pack.
It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date.

- Do not use Losec if the packaging is torn or shows signs of tampering.

- Do not use it to treat any other complaints unless your doctor says to.

- Do not give this medicine to anyone else, even if their symptoms seem similar to yours.

Things you must do - Use Losec exactly as your doctor has prescribed. - Tell all doctors, dentists and pharmacists who are treating you that you are taking Losec. - Tell your doctor if you become pregnant while you are taking Losec.

Telephone your doctor or the Poisons Information Centre or go to casualty at your nearest hospital immediately if you think that you or anyone else may have taken too much Losec even if there are no signs of discomfort or poisoning.
While you are using Losec