Is a genuine non-sedating antihistamine indicated to relieve the symptoms of hayfever allergy, such as sneezing, itchy and runny nose, itchy throat and itchy and watery eyes. Once daily is a highly convenient dosing schedule and Telfast’s non-sedating character makes it ideal for environments where you don’t want to run the risk of being drowsy.
How does TELFAST work?
Fexofenadine belongs to a group of medicines called non-sedating antihistamines.
Histamine is a chemical produced by the body. It is stored in cells (mast cells) in almost all tissues of the body. When the body reacts to a foreign substance (an allergen e.g. flower pollen), the mast cells release their stores of histamine.
Histamine may then bind to receptors (H-1 receptors) in many areas of the body causing an increased blood flow to the area of the allergy and the release of other chemicals that add to the allergic response. This stimulates the symptoms of an allergic reaction such as inflammation of the skin, airways or tissues, rashes, itching of the skin, eyes or nose, nasal congestion or narrowing of the airways.
Fexofenadine acts by blocking the binding of histamine to receptors in the body. It does not prevent the actual release of histamine from mast cells. By blocking the binding of histamine, the release of other chemicals and increased blood supply to the area is prevented or decreased. This results in prevention or relief of the typical symptoms of an allergic reaction.
Histamine may be released from and act in a small (localised) area of the body e.g the nose. Alternatively, histamine can result in a serious or complete body reaction e.g. anaphylactic reaction. Fexofenadine (120mg) is only useful for the prevention or relief of localised or less serious allergies such as hay fever (rather than very serious allergic reactions).
Fexofenadine is called a non-sedating anti-histamine as it does not enter the brain in significant quantities and is therefore unlikely to cause drowsiness. However, drowsiness may very rarely occur.
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